Researchers are merging AI and Mendelian randomization (MR) to accelerate causal inference in biomedical research. New systems like MRAgent and AI-driven GWAS data fetchers automate literature review, ...

Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits In the article that accompanies this ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

In a randomized clinical trial, instead of allocating patients equally between the treatment arms, some trials in oncology assign a higher proportion of patients to receive the experimental treatment ...

Breakthrough Designation: Pivotal Trials Lack Randomization, Double-Blinding and Control Groups A review of all therapeutics receiving a breakthrough designation and approved from 2012 to 2017 found a ...